Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566376 | 1.00 | USP2 (0.45) | USP2NPC1RAB9AL3MBTL1TRPM8 | |
| SCHEMBL7750101 | 0.91 | NPC1 (0.46) | NPC1RAB9AL3MBTL1TRPM8ALDH1A1 | |
| SCHEMBL7750096 | 0.91 | NPC1 (0.46) | NPC1RAB9AL3MBTL1TRPM8ALDH1A1 | |
| SCHEMBL8563544 | 0.87 | ALDH1A1 (0.56) | NPC1RAB9AALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL8563549 | 0.87 | ALDH1A1 (0.56) | NPC1RAB9AALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7746460 | 0.82 | NPC1 (0.51) | NPC1RAB9AL3MBTL1TRPM8ALDH1A1 | |
| SCHEMBL7746456 | 0.82 | NPC1 (0.51) | NPC1RAB9AL3MBTL1TRPM8ALDH1A1 | |
| SCHEMBL7748142 | 0.80 | MAPT (0.51) | NPC1RAB9AL3MBTL1HTTALDH1A1 | |
| SCHEMBL7748138 | 0.80 | MAPT (0.51) | NPC1RAB9AL3MBTL1HTTALDH1A1 | |
| SCHEMBL7747853 | 0.80 | NPC1 (0.47) | NPC1L3MBTL1TRPM8HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |