Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563288 | 0.88 | THRB (0.34) | THRBKMT2AMEN1TSHRNR1H4 | |
| SCHEMBL8622648 | 0.79 | CNR1 (0.40) | THRBKMT2AMEN1ZDHHC2 | |
| SCHEMBL8622651 | 0.79 | CNR1 (0.40) | THRBKMT2AMEN1ZDHHC2 | |
| SCHEMBL7020068 | 0.76 | — | — | |
| SCHEMBL7020060 | 0.76 | — | — | |
| SCHEMBL14192465 | 0.76 | THRB (0.40) | THRBKMT2AMEN1NFKB1NFKB2 | |
| SCHEMBL7026247 | 0.76 | TSHR (0.33) | KMT2AMEN1TSHR | |
| SCHEMBL7026254 | 0.76 | TSHR (0.33) | KMT2AMEN1TSHR | |
| SCHEMBL7024019 | 0.73 | TSHR (0.31) | KMT2AMEN1TSHR | |
| SCHEMBL7024024 | 0.73 | TSHR (0.31) | KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929509-A1 | LIQUID CRYSTAL ALKENYL BICYCLO 2.2.2]OCTANES AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013326-A1 | LIQUID CRYSTAL ALKENYL BICYCLO[2.2.2]OCTANES AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1998-04-02 | — | — | WO | disclosed |