SCHEMBL8622651

SCHEMBL8622651

CCCCCC=CC(=O)Oc1ccc(C23CCC(CCCCC)(CC2)CC3)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 7/20 0.40
CNR2 P34972 5/20 0.40
THRB P10828 1/20 0.37
STS P08842 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PSMB11 A5LHX3 1/20 0.34
PSMA7 O14818 1/20 0.34
PSMB1 P20618 1/20 0.34
PSMA1 P25786 1/20 0.34
PSMA2 P25787 1/20 0.34
PSMA3 P25788 1/20 0.34
PSMA4 P25789 1/20 0.34
PSMB8 P28062 1/20 0.34
PSMB9 P28065 1/20 0.34
PSMA5 P28066 1/20 0.34
PSMB4 P28070 1/20 0.34
PSMB6 P28072 1/20 0.34
PSMB5 P28074 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8622648 1.00 CNR1 (0.40) CNR1CNR2THRBSTSZDHHC2
SCHEMBL8563288 0.83 THRB (0.34) THRBZDHHC2MEN1KMT2A
SCHEMBL7022480 0.80 KMT2A (0.42) THRBSTSMEN1KMT2A
SCHEMBL7027510 0.80 STS (0.36) CNR1CNR2STSMEN1KMT2A
SCHEMBL8519888 0.80 KMT2A (0.51) STSMEN1KMT2A
SCHEMBL7027522 0.80 STS (0.36) CNR1CNR2STSMEN1KMT2A
SCHEMBL8563580 0.79 THRB (0.35) THRBZDHHC2MEN1KMT2A
SCHEMBL7024294 0.79 STS (0.36) CNR1CNR2STSMEN1KMT2A
SCHEMBL7024288 0.79 STS (0.36) CNR1CNR2STSMEN1KMT2A
SCHEMBL7021772 0.78 LTA4H (0.35) CNR1CNR2PSMB11PSMA7PSMB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0929509-A1 LIQUID CRYSTAL ALKENYL BICYCLO 2.2.2]OCTANES AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS THE SECRETARY OF STATE FOR DEFENCE (GB) 1999-07-21 EP disclosed
WO-1998013326-A1 LIQUID CRYSTAL ALKENYL BICYCLO[2.2.2]OCTANES AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS THE SECRETARY OF STATE FOR DEFENCE (GB) 1998-04-02 WO disclosed