Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639574 | 0.75 | DPP4 (0.41) | DPP4AKR1C1 | |
| SCHEMBL3553606 | 0.72 | AKR1C1 (0.42) | DPP4AKR1C1 | |
| SCHEMBL1828073 | 0.72 | BACE1 (0.42) | DPP4AKR1C1 | |
| SCHEMBL42115 | 0.69 | — | — | |
| SCHEMBL4721573 | 0.68 | SLC6A4 (0.37) | DPP4AKR1C1 | |
| SCHEMBL2204048 | 0.68 | TSHR (0.36) | DPP4AKR1C1 | |
| SCHEMBL7095956 | 0.67 | — | — | |
| SCHEMBL20104825 | 0.67 | — | — | |
| SCHEMBL7741012 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL7307173 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853617-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | Novartis AG (CH) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997008155-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | disclosed |