Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5760516 | 0.89 | SLC6A3 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1862897 | 0.86 | LMNA (0.39) | OPRM1OPRD1LMNANPSR1 | |
| SCHEMBL1866642 | 0.80 | ALDH1A1 (0.40) | SLC6A2SLC6A4SLC6A3OPRM1OPRD1 | |
| SCHEMBL1862411 | 0.80 | ALDH1A1 (0.40) | SLC6A2SLC6A4SLC6A3OPRM1OPRD1 | |
| SCHEMBL8563608 | 0.75 | DPP4 (0.42) | DPP4AKR1C1 | |
| SCHEMBL1828073 | 0.75 | BACE1 (0.42) | DPP4AKR1C1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3553606 | 0.75 | AKR1C1 (0.42) | DPP4AKR1C1GRIN2DGRIN3BCYP2B6 | |
| SCHEMBL1865507 | 0.72 | ALDH1A1 (0.42) | SLC6A2SLC6A4SLC6A3OPRM1OPRD1 | |
| SCHEMBL5134021 | 0.71 | MEN1 (0.37) | DPP4 | |
| SCHEMBL2204048 | 0.71 | TSHR (0.36) | DPP4AKR1C1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292735-B1 | PROCESS FOR PREPARING ALPHA-(ALKYLPHENYL)-4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINE BUTANOL | ERREGIERRE INDUSTRIA CHIMICA Spa (IT) | 1992-08-19 | — | — | EP | disclosed |