Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CCR10 | P46092 | 2/20 | 0.32 |
| ▸ | TYMP | P19971 | 3/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131546 | 0.90 | KMT2A (0.45) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL8564815 | 0.86 | CA12 (0.39) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL8716222 | 0.82 | CA12 (0.39) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL8716200 | 0.82 | CA12 (0.39) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL6131660 | 0.80 | CA12 (0.48) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL6131613 | 0.79 | LMNA (0.47) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL8558881 | 0.79 | KMT2A (0.47) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL5312475 | 0.78 | KMT2A (0.41) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL6131605 | 0.77 | CA12 (0.46) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL8741533 | 0.77 | CA12 (0.39) | KMT2ACA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808091-A | DIAGNOSTIC IMAGING AGENT | BRACCO INTERNATIONAL B.V. | 1998-09-15 | — | — | US | disclosed |
| US-5688487-A | Diagnostic imaging methods using rhenium and technetium complexes containing a hypoxia-localizing moiety | BRACCO INTERNATIONAL B.V. (NL) | 1997-11-18 | — | — | US | disclosed |