Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 5/20 | 0.33 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA9 | Q16790 | 5/20 | 0.33 |
| ▸ | TYMP | P19971 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131623 | 0.93 | KMT2A (0.54) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL5316299 | 0.81 | KMT2A (0.41) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL5313313 | 0.81 | KMT2A (0.41) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL8563820 | 0.79 | KMT2A (0.42) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL6131548 | 0.78 | CA12 (0.44) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL6131613 | 0.76 | LMNA (0.47) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL11348169 | 0.75 | KMT2A (0.62) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL5310582 | 0.74 | KMT2A (0.45) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL3843843 | 0.74 | KMT2A (0.45) | KMT2ALMNATHRBCYP2C19CYP3A4 | |
| SCHEMBL5311355 | 0.74 | KMT2A (0.45) | KMT2ALMNATHRBCYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808091-A | DIAGNOSTIC IMAGING AGENT | BRACCO INTERNATIONAL B.V. | 1998-09-15 | — | — | US | disclosed |
| US-5688487-A | Diagnostic imaging methods using rhenium and technetium complexes containing a hypoxia-localizing moiety | BRACCO INTERNATIONAL B.V. (NL) | 1997-11-18 | — | — | US | disclosed |