Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561757 | 0.81 | PKM (0.45) | PKMKDM4EALDH1A1SLC2A1MAPK1 | |
| SCHEMBL8562506 | 0.81 | PKM (0.48) | PKMKDM4EALDH1A1SLC2A1MAPK1 | |
| SCHEMBL8570365 | 0.79 | PKM (0.47) | PKMKDM4EALDH1A1SLC2A1MAPK1 | |
| SCHEMBL14655775 | 0.77 | TAAR1 (0.56) | PKMHTR2A | |
| SCHEMBL8563305 | 0.77 | PKM (0.50) | PKMKDM4EALDH1A1SLC2A1MAPK1 | |
| SCHEMBL29543480 | 0.77 | TAAR1 (0.56) | PKMHTR2A | |
| SCHEMBL8561635 | 0.77 | SLC2A1 (0.44) | PKMKDM4EALDH1A1SLC2A1MAPK1 | |
| SCHEMBL3577502 | 0.75 | PKM (0.53) | PKMKDM4EALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9971029 | 0.75 | PKM (0.53) | PKMKDM4EALDH1A1SLC2A1MAPK1 | |
| Bromide SCHEMBL22778255 | 0.73 | PKM (0.49) | PKMKDM4EALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549366-B1 | Thiazolidine compounds containing a quinone group, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-04-15 | — | — | EP | disclosed |
| CN-1033639-C | Benzoquinonyl-containing thiazolidine compound, preparing process thereof and its application in medicine | SANKYO CO (JP) | 1996-12-25 | — | — | CN | disclosed |
| CN-1032751-C | thiazolidine compounds, their preparation and their therapeutic use | SANKYO CO (JP) | 1996-09-11 | — | — | CN | disclosed |
| EP-0549365-B1 | Thiazolidine compounds, their preparation and their therapeutic uses | SANKYO CO (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5338855-A | Treating diabetes or hyperlipemia | SANKYO COMPANY, LIMITED (JP) | 1994-08-16 | — | — | US | disclosed |
| CN-1074679-A | Its preparation of thiazolidine compound and the therepic use thereof that contain quinonyl | SANKYO CO (JP) | 1993-07-28 | — | — | CN | disclosed |
| CN-1074680-A | Thiazolidine compound, its preparation and therepic use thereof | SANKYO CO (JP) | 1993-07-28 | — | — | CN | disclosed |
| EP-0549366-A1 | Thiazolidine compounds containing a quinone group, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | disclosed |
| EP-0549365-A1 | Thiazolidine compounds, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | disclosed |