Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014329 | 0.91 | HRH3 (0.43) | HRH3GNAO1GBA1HRH4GNAI3 | |
| SCHEMBL332080 | 0.84 | GNAO1 (0.45) | HRH3GNAO1GBA1HRH4GNAI3 | |
| Hydrochloric Acid SCHEMBL4486629 | 0.81 | GNAO1 (0.48) | HRH3GNAO1GBA1GNAI3GNAI1 | |
| Hydrochloric Acid SCHEMBL3670602 | 0.81 | GNAO1 (0.48) | HRH3GNAO1GBA1GNAI3GNAI1 | |
| SCHEMBL9384345 | 0.81 | GNAO1 (0.44) | HRH3GNAO1GBA1HRH4GNAI3 | |
| SCHEMBL8097693 | 0.76 | ITGB3 (0.46) | HRH3GNAO1GBA1GNAI3GNAI1 | |
| SCHEMBL7957882 | 0.74 | CYP1A2 (0.44) | HRH3GNAO1GBA1 | |
| SCHEMBL1706687 | 0.74 | — | — | |
| SCHEMBL11636554 | 0.73 | CYP1A2 (0.36) | — | |
| SCHEMBL237382 | 0.73 | ITGB3 (0.47) | HRH3GNAO1GBA1GNAI3GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863899-A1 | PYRIDOPYRIMIDINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997019946-A1 | PYRIDOPYRIMIDINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |