Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 6/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560074 | 0.92 | AVPR2 (0.48) | AVPR2AVPR1A | |
| SCHEMBL8561799 | 0.91 | AVPR2 (0.59) | AVPR2AVPR1A | |
| SCHEMBL8557390 | 0.90 | AVPR2 (0.52) | AVPR2AVPR1A | |
| SCHEMBL8557947 | 0.89 | AVPR2 (0.53) | AVPR2AVPR1A | |
| SCHEMBL8556991 | 0.86 | AVPR2 (0.58) | AVPR2AVPR1A | |
| SCHEMBL8562699 | 0.85 | AVPR2 (0.39) | AVPR2AVPR1AAKT1 | |
| SCHEMBL8558202 | 0.85 | HTR1F (0.51) | AVPR2AVPR1A | |
| SCHEMBL8557265 | 0.84 | AVPR2 (0.58) | AVPR2AVPR1A | |
| SCHEMBL8562470 | 0.84 | AVPR2 (0.40) | AVPR2AVPR1A | |
| SCHEMBL8561944 | 0.83 | AVPR2 (0.48) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |