Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564189 | 1.00 | ESR1 (0.41) | ESR1ESR2HDAC6ABHD6NR3C2 | |
| SCHEMBL8567424 | 0.87 | ESR1 (0.40) | ESR1ESR2HDAC6ABHD6DRD3 | |
| SCHEMBL8567428 | 0.87 | ESR1 (0.40) | ESR1ESR2HDAC6ABHD6DRD3 | |
| SCHEMBL8568710 | 0.86 | F10 (0.39) | ESR1ESR2 | |
| SCHEMBL8561412 | 0.86 | ESR1 (0.41) | ESR1ESR2HDAC6ABHD6PDE4B | |
| SCHEMBL8568715 | 0.86 | F10 (0.39) | ESR1ESR2 | |
| SCHEMBL8561418 | 0.86 | ESR1 (0.41) | ESR1ESR2HDAC6ABHD6PDE4B | |
| SCHEMBL7469615 | 0.85 | ESR1 (0.38) | ESR1ESR2HDAC6ABHD6NR3C2 | |
| SCHEMBL7469620 | 0.85 | ESR1 (0.38) | ESR1ESR2HDAC6ABHD6NR3C2 | |
| Hydrochloric Acid SCHEMBL8595133 | 0.84 | HTR6 (0.39) | HTR1ADRD3HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612741-B1 | Cyclic derivatives, medicaments containing them and process for their preparation | THOMAE GMBH DR K (DE) | 1998-06-10 | — | — | EP | disclosed |
| US-5612335-A | ANTICOAGULANTS; COMBATING/PREVENTING DISEASES WHERE CELL AGGREGATES OCCUR OR CELL-MATRIX INTERACTIONS PLAY A PART | KARL THOMAE GMBH (DE) | 1997-03-18 | — | — | US | disclosed |
| US-5519036-A | IMIDAZOLIDINONES, ANTICOAGULANTS, CELL AGGREGATION PREVENTION | KARL THOMAE GMBH (DE) | 1996-05-21 | — | — | US | disclosed |
| EP-0612741-A1 | Cyclic derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-08-31 | — | — | EP | disclosed |