Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564264 | 1.00 | DDB1 (0.50) | DDB1CRBNALDH1A1HDAC1HDAC8 | |
| SCHEMBL16874753 | 0.90 | L3MBTL1 (0.51) | DDB1CRBNALDH1A1HDAC1HDAC8 | |
| SCHEMBL1542776 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SIGMAR1KMT2AMEN1 | |
| SCHEMBL8564961 | 0.83 | ALDH1A1 (0.53) | ALDH1A1POLB | |
| SCHEMBL8564966 | 0.83 | ALDH1A1 (0.53) | ALDH1A1POLB | |
| SCHEMBL16874550 | 0.83 | KCNH2 (0.51) | KMT2AMEN1 | |
| SCHEMBL27485081 | 0.83 | PTGS1 (0.46) | ALDH1A1HDAC1HDAC8HDAC6L3MBTL1 | |
| SCHEMBL16885927 | 0.82 | MEN1 (0.57) | ALDH1A1ACHEKMT2APOLBMEN1 | |
| SCHEMBL8567054 | 0.82 | ALDH1A1 (0.55) | ALDH1A1SIGMAR1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL8567056 | 0.82 | ALDH1A1 (0.55) | ALDH1A1SIGMAR1KMT2ACYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-08 | — | — | US | disclosed |
| EP-0761673-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |