Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.39 |
| ▸ | BLM | P54132 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563573 | 0.93 | ADRB2 (0.41) | ADRA1ASLC6A2HTR1ASLC6A4ADRB2 | |
| SCHEMBL8558864 | 0.85 | ADRB2 (0.39) | ADRA1ASLC6A2HTR1ASLC6A4ADRB2 | |
| SCHEMBL8559579 | 0.85 | ADRB2 (0.39) | ADRA1ASLC6A2HTR1ASLC6A4ADRB2 | |
| SCHEMBL8557371 | 0.82 | ADRB2 (0.45) | ADRA1ASLC6A2ADRB2KDM4EMAPT | |
| SCHEMBL8559210 | 0.82 | ADRB2 (0.61) | ADRA1ASLC6A2HTR1ASLC6A4ADRB2 | |
| SCHEMBL8559213 | 0.82 | ADRB2 (0.61) | ADRA1ASLC6A2HTR1ASLC6A4ADRB2 | |
| Oxalic Acid SCHEMBL8564309 | 0.81 | ADRB2 (0.56) | ADRA1ASLC6A2HTR1ASLC6A4ADRB2 | |
| Oxalic Acid SCHEMBL8564305 | 0.81 | ADRB2 (0.56) | ADRA1ASLC6A2HTR1ASLC6A4ADRB2 | |
| Oxalic Acid SCHEMBL8563561 | 0.74 | ADRB2 (0.58) | ADRA1ASLC6A2HTR1ASLC6A4ADRB2 | |
| Oxalic Acid SCHEMBL8633452 | 0.74 | ADRB2 (0.58) | ADRA1ASLC6A2HTR1ASLC6A4ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5775329-A | DERIVATIVES OF NOREPINEPHRINE USED TO STIMULATE EXERCISE STRESS AND ITS EFFECTS ON THE HEART. | GENSIA, INC. (US) | 1998-07-07 | — | — | US | disclosed |