Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566789 | 0.86 | GABRP (0.50) | ALDH1A1LMNAMAPTCYP3A4KMT2A | |
| SCHEMBL8561878 | 0.85 | GABRP (0.41) | ALDH1A1LMNAMAPTCYP3A4KMT2A | |
| SCHEMBL30287108 | 0.81 | CYP3A4 (0.45) | ALDH1A1LMNAMAPTCYP3A4BLM | |
| SCHEMBL801341 | 0.81 | CYP3A4 (0.45) | ALDH1A1LMNAMAPTCYP3A4BLM | |
| SCHEMBL28406699 | 0.81 | SIRT6 (0.44) | ALDH1A1MAPTGABRPGABRDGABRA1 | |
| SCHEMBL8564866 | 0.77 | EGFR (0.41) | ALDH1A1LMNAMAPTCYP3A4KMT2A | |
| SCHEMBL8564092 | 0.77 | MAPK1 (0.47) | ALDH1A1MAPTCYP3A4PMP22KMT2A | |
| SCHEMBL780203 | 0.76 | MAPT (0.58) | ALDH1A1LMNAMAPTCYP3A4BLM | |
| SCHEMBL5252473 | 0.76 | TDP1 (0.48) | ALDH1A1LMNAMAPTCYP3A4KMT2A | |
| SCHEMBL8598549 | 0.75 | GABRP (0.43) | ALDH1A1LMNAMAPTCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |