SCHEMBL8564402

SCHEMBL8564402

CCN(CC)CCOC(=O)Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.47
CYP2D6 P10635 3/20 0.47
TSHR P16473 3/20 0.47
MAOA P21397 2/20 0.47
HTR3A P46098 2/20 0.47
HRH3 Q9Y5N1 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP3A4 P08684 3/20 0.46
NPSR1 Q6W5P4 2/20 0.46
BLM P54132 1/20 0.46
ALDH1A1 P00352 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CHRM2 P08172 5/20 0.45
CHRM3 P20309 4/20 0.45
CHRM1 P11229 3/20 0.45
SCN1A P35498 3/20 0.45
SCN2A Q99250 3/20 0.45
SCN3A Q9NY46 3/20 0.45
CHRM4 P08173 2/20 0.45
CHRM5 P08912 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4814939 0.98 NPSR1 (0.49) LMNACYP2D6TSHRMAOAHTR3A
SCHEMBL8561639 0.87 CHRM2 (0.45) LMNACYP2D6TSHRMAOAHTR3A
SCHEMBL8565781 0.84 CYP2D6 (0.49) LMNACYP2D6HTR3AHRH3CYP1A2
SCHEMBL25380908 0.81 LMNA (0.50) LMNACYP2D6TSHRMAOAHTR3A
SCHEMBL7058546 0.81 LMNA (0.50) LMNACYP2D6TSHRMAOAHTR3A
SCHEMBL454947 0.79 ALDH1A1 (0.50) LMNACYP2D6TSHRMAOAHTR3A
SCHEMBL14793306 0.79 LMNA (0.49) LMNACYP2D6TSHRMAOAHTR3A
Hydrochloric Acid SCHEMBL8399789 0.79 SCN5A (0.53) LMNACYP2D6TSHRMAOAHTR3A
SCHEMBL4410359 0.79 CYP2D6 (0.53) LMNACYP2D6TSHRMAOAHTR3A
SCHEMBL11025270 0.78 CYP2D6 (0.45) LMNACYP2D6TSHRMAOAHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5705497-A INOTROPIC, ANTIARRHYTHMIA AGENTS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1998-01-06 US disclosed
US-4958024-A REACTION OF CARBAMATE SUBSTITUTED ACRYLIC ESTER, VASODILATORS, HYPOTENSIVE AGENTS BANYU PHARMACEUTICAL COMPANY, LTD. (JP) 1990-09-18 US disclosed
US-4914227-A FOR VASODILATING AND HYPOTENSIVE AGENTS BANYU PHARMACEUTICAL COMPANY, LTD. (JP) 1990-04-03 US disclosed
US-4739106-A VASODILATION, HYPOTENSIVE AGENTS BANYU PHARMACEUTICAL CO., LTD. (JP) 1988-04-19 US disclosed
EP-0101023-B1 PROCESS FOR PREPARING 2-CARBAMOYLOXYALKYL-1,4-DIHYDROPYRIDINE DERIVATIVES AND INTERMEDIATES USEFUL FOR THE PROCESS BANYU PHARMACEUTICAL CO., LTD. (JP) 1987-07-29 EP disclosed
EP-0101023-A1 Process for preparing 2-carbamoyloxyalkyl-1,4-dihydropyridine derivatives and intermediates useful for the process BANYU PHARMACEUTICAL CO., LTD. (JP) 1984-02-22 EP disclosed