Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930941 | 0.86 | CYP1A2 (0.51) | CYP1A2CYP2D6HTTPOLBTLR8 | |
| Hydrochloric Acid SCHEMBL6934110 | 0.84 | CYP1A2 (0.50) | CYP1A2CYP2D6HTTPOLBTLR8 | |
| SCHEMBL1980314 | 0.80 | HSD17B10 (0.57) | CYP1A2CYP2D6HTTPOLBNOD1 | |
| SCHEMBL21310919 | 0.80 | KDM4E (0.57) | CYP1A2CYP2D6HTTPOLBTLR8 | |
| SCHEMBL7847984 | 0.79 | NOS2 (0.55) | CYP1A2CYP2D6HTTPOLBTLR8 | |
| Bromide SCHEMBL1982279 | 0.79 | HSD17B10 (0.56) | CYP1A2CYP2D6HTTPOLBNOD1 | |
| SCHEMBL8932209 | 0.78 | MEN1 (0.42) | CYP1A2POLBKDM4EALDH1A1HPGD | |
| SCHEMBL6934460 | 0.78 | S1PR1 (0.41) | CYP1A2HTTPOLBNOD1CXCL8 | |
| SCHEMBL7847769 | 0.78 | HTT (0.57) | CYP1A2CYP2D6HTTPOLBTLR8 | |
| SCHEMBL7848302 | 0.75 | POLB (0.55) | CYP1A2CYP2D6HTTPOLBTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571253-B1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR (FR) | 1998-11-04 | — | — | EP | disclosed |
| US-5639756-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-06-17 | — | — | US | disclosed |
| US-5623073-A | ANTIDIABETIC AGENT | ADIR ET COMPAGNIE (FR) | 1997-04-22 | — | — | US | disclosed |
| EP-0571253-A1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR ET COMPAGNIE (FR) | 1993-11-24 | — | — | EP | disclosed |