SCHEMBL8564540

SCHEMBL8564540

CCOc1n[c]ncc1C

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
MAPT P10636 1/20 0.31
LRRK2 Q5S007 1/20 0.31
MEN1 O00255 1/20 0.30
NQO1 P15559 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1526049 0.78 HPGD (0.34) HPGDSMN1; SMN2KDM4EALDH1A1
SCHEMBL8564428 0.78 NUDT1 (0.36) KMT2AKDM4EALDH1A1MAPTMEN1
SCHEMBL558256 0.77
SCHEMBL500142 0.68
SCHEMBL663821 0.67
SCHEMBL500322 0.66
SCHEMBL1471867 0.65 KMT2A (0.45) HPGDSMN1; SMN2KMT2AKDM4EALDH1A1
SCHEMBL957692 0.65 HPGD (0.32) HPGDSMN1; SMN2LRRK2NQO1
SCHEMBL18072298 0.64 NUDT1 (0.66) KDM4E
SCHEMBL3391484 0.64 KDM4E (0.31) HPGDKDM4EALDH1A1MAPTNQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0586393-B1 SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES ZENECA LTD (GB) 1998-06-17 EP claimed
US-5439910-A For applying to plants, seeds or soils ZENECA LIMITED (GB) 1995-08-08 US claimed