Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469010 | 1.00 | MTNR1A (0.55) | MTNR1AMTNR1BMEN1KMT2ASLC6A2 | |
| SCHEMBL30576519 | 1.00 | MTNR1A (0.55) | MTNR1AMTNR1BMEN1KMT2ASLC6A2 | |
| SCHEMBL8564551 | 1.00 | MTNR1A (0.55) | MTNR1AMTNR1BMEN1KMT2ASLC6A2 | |
| SCHEMBL13305786 | 0.86 | MTNR1A (0.52) | MTNR1AMTNR1BMEN1KMT2ASLC6A2 | |
| SCHEMBL11639091 | 0.82 | MTNR1A (0.42) | MTNR1AMTNR1BMEN1KMT2AALOX15 | |
| SCHEMBL7422361 | 0.81 | MTNR1A (0.59) | MTNR1AMTNR1BMEN1KMT2AEPHX2 | |
| SCHEMBL16353622 | 0.81 | MTNR1A (0.59) | MTNR1AMTNR1BMEN1KMT2AEPHX2 | |
| SCHEMBL7422364 | 0.81 | MTNR1A (0.59) | MTNR1AMTNR1BMEN1KMT2AEPHX2 | |
| SCHEMBL2036744 | 0.81 | MTNR1A (0.59) | MTNR1AMTNR1BMEN1KMT2AEPHX2 | |
| SCHEMBL28138448 | 0.81 | MTNR1A (0.55) | MTNR1AMTNR1BMEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |