Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422361 | 1.00 | MTNR1A (0.59) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL18576830 | 0.82 | MTNR1A (0.56) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8562575 | 0.82 | MTNR1A (0.52) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8562578 | 0.82 | MTNR1A (0.52) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8562571 | 0.82 | MTNR1A (0.52) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL7835228 | 0.82 | MTNR1A (0.52) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL16353622 | 0.81 | MTNR1A (0.59) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL2036744 | 0.81 | MTNR1A (0.59) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL30576519 | 0.81 | MTNR1A (0.55) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL8564553 | 0.81 | MTNR1A (0.55) | MTNR1AMTNR1BEPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |