SCHEMBL8564899

SCHEMBL8564899

CCCCc1csc(CCCC)c1CCCC

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.35
NPC1 O15118 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
GPR35 Q9HC97 5/20 0.33
TYR P14679 2/20 0.33
CTRC Q99895 1/20 0.31
MAPT P10636 1/20 0.30
KDM4E B2RXH2 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2830601 0.92 GPR35 (0.41) HTTGPR35TYRMAPT
SCHEMBL28681510 0.92 GPR35 (0.41) HTTGPR35TYRMAPT
SCHEMBL3331501 0.92 GPR35 (0.41) HTTGPR35TYRMAPT
Hydrochloric Acid SCHEMBL28626178 0.87 HTR2A (0.34) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL2754798 0.86 NPC1 (0.32) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL2754801 0.86 NPC1 (0.36) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL2754799 0.81 HTT (0.36) HTTNPC1HPGDMAPK1RAB9A
Tetrahydrofuran SCHEMBL29110538 0.81 GPR35 (0.35) GPR35TYR
Chlorobenzene SCHEMBL29110540 0.79 LIPG (0.40) GPR35TYR
SCHEMBL8557305 0.78 HMGCR (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110752336-A Voltage sensitive polymer diaphragm and preparation method thereof 中国科学院金属研究所 2020-02-04 CN claimed
CN-108963229-B High-performance silicon negative electrode active material and preparation method thereof 中国科学院金属研究所 2021-03-26 CN disclosed
CN-108807797-B Overcharge-preventing lithium battery composite diaphragm and preparation method thereof 中国科学院金属研究所 2020-03-20 CN disclosed
CN-110752336-A Voltage sensitive polymer diaphragm and preparation method thereof 中国科学院金属研究所 2020-02-04 CN disclosed
CN-108963229-A A kind of high performance silicon negative electrode active material and preparation method thereof 中国科学院金属研究所 2018-12-07 CN disclosed
CN-108807797-A A kind of anti-overcharge lithium electricity composite diaphragm and preparation method thereof 中国科学院金属研究所 2018-11-13 CN disclosed
CN-108516985-A Double fluorine boron hyperfluorescence dyestuffs of pyrroles's hydrazine and its preparation method and application 安徽师范大学 2018-09-11 CN disclosed
CN-103811185-B Organic dye compound and dye-sensitized solar cell comprising same 大邱庆北科学技术院 2017-03-01 CN disclosed
CN-102807579-B Quinacridone derivative boric acid ester and preparation method thereof and application INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2015-09-02 CN disclosed
CN-102816177-B Quinacridone borate, and preparation method and application thereof CHINESE ACAD INST CHEMISTRY 2015-07-01 CN disclosed
CN-1030450-C Preparation of analgesic carboxylic acid amides derivative SANKYO CO (JP) 1995-12-06 CN disclosed
CN-1079740-A The preparation method of analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1993-12-22 CN disclosed
CN-1079741-A The preparation method of analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1993-12-22 CN disclosed
US-5270327-A Piperidine derivatives SANKYO COMPANY, LIMITED (JP) 1993-12-14 US disclosed
CN-1078461-A The preparation method of analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1993-11-17 CN disclosed
CN-1022185-C Process for preparing analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1993-09-22 CN disclosed
EP-0356247-B1 ANALGESIC CARBOXYLIC ACID AMIDE DERIVATIVES Sankyo Company Limited (JP) 1993-03-17 EP disclosed
US-5021413-A Analgesic thiomorpholins their preparation, and pharmaceutical compositions containing them SANKYO COMPANY LIMITED (JP) 1991-06-04 US disclosed
CN-1040791-A ANALGESIC CARBOXYLIC ACID AMIDE DERIVATIVES SANKYO CO (JP) 1990-03-28 CN disclosed
EP-0356247-A1 Analgesic carboxylic acid amide derivatives Sankyo Company Limited (JP) 1990-02-28 EP disclosed