Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3057430 | 0.86 | ALDH1A1 (0.63) | ALDH1A1KDM4EHSD17B10CA12CA1 | |
| SCHEMBL11165767 | 0.83 | ALDH1A1 (0.76) | ALDH1A1KDM4EHSD17B10CA12CA1 | |
| SCHEMBL28777916 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10CA12CA1 | |
| SCHEMBL29869602 | 0.81 | CA12 (0.48) | ALDH1A1KDM4EHSD17B10CA12CA1 | |
| SCHEMBL7014801 | 0.81 | CA12 (0.48) | ALDH1A1KDM4EHSD17B10CA12CA1 | |
| SCHEMBL22993287 | 0.81 | CA12 (0.48) | ALDH1A1KDM4EHSD17B10CA12CA1 | |
| SCHEMBL6828227 | 0.81 | CA12 (0.48) | ALDH1A1KDM4EHSD17B10CA12CA1 | |
| SCHEMBL10581550 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10CA12CA1 | |
| SCHEMBL4398094 | 0.81 | RAB9A (0.50) | ALDH1A1KDM4EHSD17B10CA12CA1 | |
| SCHEMBL203402 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |
| US-3985799-A | 2-Fluoro-6-trifluoromethylbenzoic acid | SANDOZ, INC. (US) | 1976-10-12 | — | — | US | disclosed |