Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HSD3B1 | P14060 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569642 | 1.00 | MBOAT4 (0.40) | MBOAT4GPR84GRIN1GRIN2BABCC4 | |
| SCHEMBL5580932 | 0.96 | MBOAT4 (0.41) | MBOAT4GRIN1GRIN2BABCC4ABCB11 | |
| SCHEMBL9134492 | 0.81 | MBOAT4 (0.40) | MBOAT4GRIN1GRIN2BABCC4ABCB11 | |
| SCHEMBL10698417 | 0.81 | MBOAT4 (0.45) | MBOAT4GRIN1GRIN2BABCC4ABCB11 | |
| SCHEMBL4807036 | 0.80 | MBOAT4 (0.47) | MBOAT4GRIN1GRIN2BABCC4ABCB11 | |
| SCHEMBL8564985 | 0.79 | CYP19A1 (0.34) | MBOAT4GPR84GRIN1GRIN2BABCC4 | |
| SCHEMBL8571736 | 0.79 | CYP19A1 (0.34) | MBOAT4GPR84GRIN1GRIN2BABCC4 | |
| SCHEMBL8978606 | 0.79 | MBOAT4 (0.39) | MBOAT4GRIN1GRIN2BCYP3A4 | |
| SCHEMBL9235530 | 0.78 | MBOAT4 (0.39) | MBOAT4GRIN1GRIN2BABCC4ABCB11 | |
| SCHEMBL9618180 | 0.76 | SRD5A1 (0.44) | MBOAT4GRIN1GRIN2BSRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817818-A | THERAPY OF ANDROGEN RESPONSIVE DISEASES | GLAXO WELLCOME INC. (US) | 1998-10-06 | — | — | US | disclosed |