Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.50 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | PPARD | Q03181 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | TERT | O14746 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | F7 | P08709 | 3/20 | 0.40 |
| ▸ | F3 | P13726 | 3/20 | 0.40 |
| ▸ | TOP1 | P11387 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL1868934 | 0.85 | PTGS1 (0.39) | PPARGMAPTCYP19A1FFAR1PPARD | |
| SCHEMBL8744195 | 0.83 | NAAA (0.44) | ALDH1A1BLMHSD17B10LMNACYP1A2 | |
| SCHEMBL8744192 | 0.83 | NAAA (0.44) | ALDH1A1BLMHSD17B10LMNACYP1A2 | |
| SCHEMBL11292223 | 0.83 | NAAA (0.44) | ALDH1A1BLMHSD17B10LMNACYP1A2 | |
| SCHEMBL17607293 | 0.82 | PTGS1 (0.36) | PPARGMAPTCYP19A1ALDH1A1RXRA | |
| SCHEMBL873462 | 0.82 | NAAA (0.42) | MAPTALDH1A1PTGS1BLMHSD17B10 | |
| SCHEMBL2039597 | 0.82 | NAAA (0.42) | MAPTALDH1A1PTGS1BLMHSD17B10 | |
| SCHEMBL873463 | 0.82 | NAAA (0.42) | MAPTALDH1A1PTGS1BLMHSD17B10 | |
| SCHEMBL30870406 | 0.80 | NAAA (0.45) | MAPTALDH1A1PTGS1BLMHSD17B10 | |
| SCHEMBL5385680 | 0.80 | PPARG (0.48) | PPARGMAPTCYP19A1ALDH1A1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718273-B1 | Ethyl 6-formyloxy-4-hexenoate | MERRELL PHARMA INC (US) | 1998-03-11 | — | — | EP | disclosed |