Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490662 | 0.78 | CYP4F2 (0.42) | CYP4F2CYP4A11AKT1 | |
| SCHEMBL18298939 | 0.75 | CYP4F2 (0.38) | CYP4F2CYP4A11 | |
| SCHEMBL18300644 | 0.74 | SSTR4 (0.34) | AAK1 | |
| SCHEMBL16529032 | 0.73 | CYP4F2 (0.43) | CYP4F2CYP4A11 | |
| SCHEMBL30896676 | 0.72 | KMT2A (0.36) | MT-CO2AKT1 | |
| SCHEMBL15755068 | 0.72 | AAK1 (0.41) | AAK1 | |
| SCHEMBL6962533 | 0.72 | FSCN1 (0.50) | CYP4F2CYP4A11 | |
| SCHEMBL21079102 | 0.71 | MT-CO2 (0.32) | MT-CO2AAK1 | |
| SCHEMBL29069653 | 0.71 | SSTR4 (0.32) | MT-CO2 | |
| SCHEMBL8562693 | 0.70 | FSCN1 (0.33) | CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5750699-A | HALOGENATING OF CORRESPONDING COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5574042-A | ANTAGONIST FOR BRADYKININS AS ANTIALLERGENS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, SHOCK OR PAIN | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |