Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSCN1 | Q16658 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962533 | 0.82 | FSCN1 (0.50) | FSCN1BDKRB2CYP4F2CYP4A11 | |
| SCHEMBL8361704 | 0.74 | BDKRB2 (0.40) | BDKRB2CYP4F2CYP4A11KDM4E | |
| SCHEMBL8565095 | 0.70 | CYP4F2 (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL9049204 | 0.70 | POLQ (0.39) | KDM4EMAPT | |
| SCHEMBL7747006 | 0.70 | POLB (0.41) | KDM4E | |
| SCHEMBL9384007 | 0.69 | FSCN1 (0.45) | FSCN1GRM5KDM4EMAPT | |
| SCHEMBL8477264 | 0.66 | GABRP (0.47) | FSCN1BDKRB2 | |
| SCHEMBL913433 | 0.65 | GSK3B (0.43) | — | |
| SCHEMBL8477267 | 0.65 | GABRP (0.46) | FSCN1BDKRB2 | |
| SCHEMBL18669200 | 0.64 | P2RX7 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5750699-A | HALOGENATING OF CORRESPONDING COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5574042-A | ANTAGONIST FOR BRADYKININS AS ANTIALLERGENS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, SHOCK OR PAIN | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |