Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28743914 | 1.00 | KDM1A (0.41) | KDM1ANOTUMMAPTSMN1; SMN2GAA | |
| SCHEMBL29651255 | 0.86 | KDM1A (0.44) | KDM1ANOTUMBCHEHDAC1HDAC6 | |
| SCHEMBL3695799 | 0.86 | KDM1A (0.44) | KDM1ANOTUMBCHEHDAC1HDAC6 | |
| SCHEMBL17221951 | 0.86 | MEN1 (0.41) | KDM1ASMN1; SMN2GAAHDAC1HDAC6 | |
| SCHEMBL17338584 | 0.85 | MAPT (0.46) | KDM1AMAPTSMN1; SMN2GAABCHE | |
| SCHEMBL29651117 | 0.84 | ALDH1A1 (0.39) | MAPTGAALMNAMEN1KMT2A | |
| SCHEMBL8562821 | 0.83 | NOTUM (0.46) | KDM1ANOTUMBCHEHDAC1HDAC6 | |
| SCHEMBL3406623 | 0.83 | NOTUM (0.46) | KDM1ANOTUMBCHEHDAC1HDAC6 | |
| SCHEMBL8016162 | 0.80 | NOTUM (0.63) | KDM1ANOTUMSMN1; SMN2BCHEHDAC1 | |
| SCHEMBL25871055 | 0.79 | KDM1A (0.45) | KDM1ANOTUMBCHEHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |