Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 8/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569026 | 0.77 | NR1H4 (0.44) | LTB4RLTB4R2NR1H4 | |
| SCHEMBL28763158 | 0.72 | CNR2 (0.43) | CNR2LTB4RLTB4R2CNR1NR1H4 | |
| SCHEMBL3813663 | 0.70 | TBXAS1 (0.37) | — | |
| SCHEMBL27694393 | 0.66 | CNR2 (0.46) | CNR2CNR1CYSLTR2CYSLTR1 | |
| SCHEMBL7819515 | 0.66 | HTR2A (0.39) | — | |
| SCHEMBL27694394 | 0.65 | CNR2 (0.46) | CNR2CNR1CYSLTR2CYSLTR1 | |
| SCHEMBL16799916 | 0.62 | MAPT (0.37) | — | |
| SCHEMBL9698367 | 0.62 | CNR2 (0.62) | CNR2CNR1 | |
| SCHEMBL29111141 | 0.61 | CNR2 (0.54) | CNR2CNR1CYSLTR2CYSLTR1 | |
| SCHEMBL27675853 | 0.61 | CNR2 (0.45) | CNR2CNR1CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544488-B1 | Substituted phenyl phenol leukotriene antagonists | LILLY CO ELI (US) | 1998-03-11 | — | — | EP | disclosed |
| CN-1035001-C | Substituted phenyl phenol leukotriene antagonists | LILLY CO ELI (US) | 1997-05-28 | — | — | CN | disclosed |
| WO-1996036347-A1 | USE OF LEUKOTRIENE ANTAGONISTS FOR ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY (US) | 1996-11-21 | — | — | WO | disclosed |
| EP-0743064-A1 | Leukotriene antagonists for use in the treatment or prevention of alzheimer's disease | ELI LILLY AND COMPANY (US) | 1996-11-20 | — | — | EP | disclosed |
| US-5462954-A | Antiinflammatory, antiallergens; treating asthma | ELI LILLY AND COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0544488-A2 | Substituted phenyl phenol leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1993-06-02 | — | — | EP | disclosed |