Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARD | Q03181 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9935060 | 1.00 | LMNA (0.54) | LMNACES2CES1CNR1CNR2 | |
| SCHEMBL25724104 | 1.00 | LMNA (0.54) | LMNACES2CES1CNR1CNR2 | |
| SCHEMBL822856 | 0.94 | LMNA (0.60) | LMNACNR1CNR2TRPV1HDAC11 | |
| Sulfuric Acid SCHEMBL28897633 | 0.93 | LMNA (0.47) | LMNACES2CES1CNR1CNR2 | |
| SCHEMBL3374822 | 0.92 | CES2 (0.48) | LMNACES2CES1CNR1GPR84 | |
| SCHEMBL284784 | 0.92 | CES2 (0.48) | LMNACES2CES1CNR1GPR84 | |
| SCHEMBL225819 | 0.92 | CES2 (0.48) | LMNACES2CES1CNR1GPR84 | |
| SCHEMBL3378863 | 0.92 | CES2 (0.48) | LMNACES2CES1CNR1GPR84 | |
| SCHEMBL16390288 | 0.92 | CES2 (0.48) | LMNACES2CES1CNR1GPR84 | |
| SCHEMBL3377092 | 0.92 | CES2 (0.48) | LMNACES2CES1CNR1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5720946-A | SYNERGISTIC EFFECT; DANDRUFF; PREVENTION ITCHING | SHISEIDO COMPANY, LTD. (JP) | 1998-02-24 | — | — | US | disclosed |