Saccharin

Saccharin

SCHEMBL8565204

O=C1NS(=O)(=O)c2ccccc21.Oc1ccccc1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.79
CA9 Q16790 6/20 0.79
CA2 P00918 5/20 0.79
CA1 P00915 2/20 0.79
KDM4E B2RXH2 1/20 0.79
USP2 O75604 1/20 0.79
LMNA P02545 1/20 0.79
BCHE P06276 1/20 0.79
CA4 P22748 1/20 0.79
CA6 P23280 1/20 0.79
CA5A P35218 1/20 0.79
CA7 P43166 1/20 0.79
KMT2A Q03164 1/20 0.79
CA14 Q9ULX7 1/20 0.79
CA5B Q9Y2D0 1/20 0.79
HSD11B1 P28845 1/20 0.51
ALDH1A1 P00352 2/20 0.51
ALPL P05186 2/20 0.50
ALPI P09923 2/20 0.50
GAA P10253 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Saccharin SCHEMBL28045129 0.93 CA12 (0.92) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL28334570 0.91 CA12 (0.88) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL29037506 0.89 CA12 (0.92) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL27905604 0.89 CA12 (0.92) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL7073018 0.89 CA12 (1.00) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL3816 0.89 CA12 (1.00) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL29191365 0.89 CA12 (1.00) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL29358404 0.89 CA12 (1.00) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL588640 0.89 CA12 (1.00) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL4777123 0.89 CA12 (1.00) CA12CA9CA2CA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101507813-A Technique for removing meningococcus polysaccharide endotoxin ZHEJIANG TIANYUAN BIO PHARMACE (CN) 2009-08-19 CN claimed
CN-109468351-A The method of efficient Enzyme catalyzed synthesis sanguinarine and Chelerythrine 湖南美可达生物资源股份有限公司 2019-03-15 CN disclosed
CN-109136220-A A kind of Fagaceae sample DNA extracts and purification process 上海应用技术大学 2019-01-04 CN disclosed
CN-106282158-A A kind of method extracting high-quality genomic DNA from Caulis et Folium Ammopiptanthi Mongolici 香港中文大学深圳研究院 2017-01-04 CN disclosed
CN-102935226-B Typhoid fever and paratyphoid fever combined vaccine and preparation method thereof LUOYI WUXI BIOLOG PHARMACEUTICAL CO LTD 2014-01-22 CN disclosed
CN-102373194-B Method for extracting RNA from tissue of Cunninghamia plant INST BOTANY CAS 2013-06-19 CN disclosed
CN-102935226-A Typhoid fever and paratyphoid fever combined vaccine and preparation method thereof LUOYI WUXI BIOLOG PHARMACEUTICAL CO LTD 2013-02-20 CN disclosed
CN-102373194-A Method for extracting RNA from tissue of Cunninghamia plant INST BOTANY CAS 2012-03-14 CN disclosed
CN-101507813-A Technique for removing meningococcus polysaccharide endotoxin ZHEJIANG TIANYUAN BIO PHARMACE (CN) 2009-08-19 CN disclosed
US-5760008-A Method and compositions for treating malignant tumors and inhibiting metastases of malignant tumors CO ENZYME TECHNOLOGY LTD. (US) 1998-06-02 US disclosed