Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565227 | 1.00 | MEN1 (0.52) | MEN1KMT2AUSP2HSD17B10CHRM3 | |
| SCHEMBL30672379 | 0.83 | BTK (0.53) | MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL13099512 | 0.83 | BTK (0.53) | MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL8320454 | 0.81 | USP2 (0.47) | MEN1KMT2AUSP2HSD17B10SMN1; SMN2 | |
| SCHEMBL6993832 | 0.79 | LMNA (0.48) | MEN1KMT2AUSP2HSD17B10CYP2D6 | |
| SCHEMBL8567460 | 0.78 | ALDH1A1 (0.54) | POLBSMN1; SMN2CYP2D6 | |
| SCHEMBL8567465 | 0.78 | ALDH1A1 (0.54) | POLBSMN1; SMN2CYP2D6 | |
| Fluorobenzene SCHEMBL27378912 | 0.78 | TACR1 (0.48) | MEN1KMT2AUSP2HSD17B10POLB | |
| SCHEMBL12495209 | 0.77 | SMN1; SMN2 (0.53) | MEN1KMT2AUSP2HSD17B10GNAI3 | |
| SCHEMBL8320450 | 0.77 | KMT2A (0.46) | MEN1KMT2AUSP2HSD17B10CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-08 | — | — | US | disclosed |
| EP-0761673-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |