Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568327 | 0.84 | MEN1 (0.39) | CA12CA1CA2CA9NPY1R | |
| SCHEMBL8566844 | 0.79 | MEN1 (0.40) | ALDH1A1MEN1KMT2AUSP2KEAP1 | |
| SCHEMBL8562112 | 0.76 | GAA (0.41) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL8601831 | 0.75 | KDM4E (0.34) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL2684700 | 0.74 | TTR (0.53) | NSD2GAAPLCG1DNMT1CASP6 | |
| SCHEMBL8596230 | 0.73 | RECQL (0.41) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL8600910 | 0.73 | TXNRD1 (0.41) | GAAL3MBTL1CA2NPY1RALDH1A1 | |
| SCHEMBL8630572 | 0.73 | CA12 (0.31) | CA12CA1CA2CA9 | |
| SCHEMBL8562255 | 0.73 | ALDH1A1 (0.51) | CA1CA2CA9NPY1RALDH1A1 | |
| SCHEMBL3029818 | 0.72 | TTR (0.51) | NSD2GAAPLCG1DNMT1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |