Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | MAP2 | P11137 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122137 | 0.74 | TRPV1 (0.45) | PTGS2TRPV1AKR1C2ALDH1A1MAPT | |
| SCHEMBL11553566 | 0.73 | AKR1C2 (0.45) | PTGS2TRPV1AKR1C2ALDH1A1MAPT | |
| SCHEMBL9359811 | 0.71 | AKR1C2 (0.62) | PTGS2AKR1C2MAPTRAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL25260391 | 0.70 | AKR1C2 (0.61) | PTGS2AKR1C2MAPTRAB9AKDM4E | |
| SCHEMBL11793036 | 0.70 | AKR1C2 (0.61) | PTGS2AKR1C2MAPTRAB9AKDM4E | |
| SCHEMBL11791916 | 0.69 | AKR1C2 (0.60) | PTGS2AKR1C2MAPTRAB9AKDM4E | |
| SCHEMBL11832981 | 0.69 | TRPV1 (0.51) | PTGS2TRPV1AKR1C2ALDH1A1MAPT | |
| SCHEMBL8686345 | 0.68 | TRPV1 (0.50) | TRPV1AKR1C2ALDH1A1MAPTNPC1 | |
| SCHEMBL8644246 | 0.68 | ALDH1A1 (0.46) | PTGS2TRPV1AKR1C2ALDH1A1MAPT | |
| SCHEMBL25260242 | 0.68 | ALDH1A1 (0.58) | PTGS2AKR1C2ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821250-A | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents | THE PROCTER & GAMBLE COMPANY (US) | 1998-10-13 | — | — | US | disclosed |