Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.31 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diatrizoic Acid SCHEMBL7615048 | 0.88 | LMNA (0.67) | LMNASMN1; SMN2TSHRMAPK1MEN1 | |
| Diatrizoic Acid SCHEMBL8508 | 0.88 | LMNA (0.67) | LMNASMN1; SMN2TSHRMAPK1MEN1 | |
| Diatrizoic Acid SCHEMBL30451079 | 0.86 | LMNA (0.65) | LMNASMN1; SMN2TSHRMAPK1MEN1 | |
| Diatrizoic Acid SCHEMBL6362397 | 0.86 | LMNA (0.65) | LMNASMN1; SMN2TSHRMAPK1MEN1 | |
| Diatrizoic Acid SCHEMBL5960726 | 0.86 | LMNA (0.65) | LMNASMN1; SMN2TSHRMAPK1MEN1 | |
| Diatrizoic Acid SCHEMBL3974126 | 0.86 | LMNA (0.65) | LMNASMN1; SMN2TSHRMAPK1MEN1 | |
| Diatrizoic Acid SCHEMBL8053758 | 0.86 | LMNA (0.65) | LMNASMN1; SMN2TSHRMAPK1MEN1 | |
| Diatrizoic Acid SCHEMBL1197801 | 0.86 | LMNA (0.65) | LMNASMN1; SMN2TSHRMAPK1MEN1 | |
| Diatrizoic Acid SCHEMBL8509 | 0.86 | LMNA (0.65) | LMNASMN1; SMN2TSHRMAPK1MEN1 | |
| SCHEMBL8752140 | 0.84 | LMNA (0.67) | LMNASMN1; SMN2TSHRMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043239-A9 | INHIBITION OF MATRIX METALLOPROTEASES BY 2-SUBSTITUTED-4-(4-SUBSTITUTEDPHENYL)-4-OXOBUTYRIC ACIDS | — | 1998-03-19 | — | — | WO | disclosed |