Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557711 | 0.85 | LMNA (0.39) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL8563358 | 0.84 | LMNA (0.36) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL6131583 | 0.84 | LMNA (0.47) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL8741531 | 0.82 | LMNA (0.36) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL8565364 | 0.77 | LMNA (0.39) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL8716249 | 0.75 | LMNA (0.35) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL8559974 | 0.75 | LMNA (0.36) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL6131569 | 0.73 | LMNA (0.55) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL8557859 | 0.73 | LMNA (0.35) | LMNATHRBCYP2C19CA12CA1 | |
| SCHEMBL6131616 | 0.72 | KMT2A (0.47) | LMNATHRBCYP2C19CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808091-A | DIAGNOSTIC IMAGING AGENT | BRACCO INTERNATIONAL B.V. | 1998-09-15 | — | — | US | disclosed |