Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565611 | 1.00 | DCUN1D1 (0.39) | DCUN1D1MCHR1ESR1ESR2MEN1 | |
| SCHEMBL8896160 | 0.95 | MCHR1 (0.41) | DCUN1D1MCHR1UBE2M | |
| SCHEMBL8896148 | 0.95 | MCHR1 (0.41) | DCUN1D1MCHR1UBE2M | |
| SCHEMBL7423187 | 0.86 | ESR1 (0.39) | DCUN1D1MCHR1ESR1ESR2UBE2M | |
| SCHEMBL8898175 | 0.75 | UBE2M (0.42) | DCUN1D1MEN1LMNAKMT2AGPR55 | |
| SCHEMBL8564198 | 0.72 | ESR1 (0.41) | ESR1ESR2L3MBTL1KDM4E | |
| SCHEMBL8564189 | 0.72 | ESR1 (0.41) | ESR1ESR2L3MBTL1KDM4E | |
| SCHEMBL8567428 | 0.71 | ESR1 (0.40) | ESR1ESR2 | |
| SCHEMBL8567424 | 0.71 | ESR1 (0.40) | ESR1ESR2 | |
| SCHEMBL8897229 | 0.70 | ESR1 (0.38) | MCHR1ESR1ESR2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |
| US-5612335-A | ANTICOAGULANTS; COMBATING/PREVENTING DISEASES WHERE CELL AGGREGATES OCCUR OR CELL-MATRIX INTERACTIONS PLAY A PART | KARL THOMAE GMBH (DE) | 1997-03-18 | — | — | US | disclosed |
| US-5519036-A | IMIDAZOLIDINONES, ANTICOAGULANTS, CELL AGGREGATION PREVENTION | KARL THOMAE GMBH (DE) | 1996-05-21 | — | — | US | disclosed |