Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Catechol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 2/20 | 0.43 |
| ▸ | THPO | P40225 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Catechol SCHEMBL2279087 | 0.86 | ALDH1A1 (0.59) | ALDH1A1TDP1ALOX15HSD17B10KDM4E | |
| Catechol SCHEMBL8563184 | 0.84 | TAAR1 (0.35) | ALDH1A1TDP1ALOX15HSD17B10KDM4E | |
| Catechol SCHEMBL6887106 | 0.83 | ALDH1A1 (0.62) | ALDH1A1TDP1ALOX15HSD17B10KDM4E | |
| Catechol SCHEMBL8562155 | 0.82 | CA12 (0.40) | ALDH1A1TDP1ALOX15HSD17B10KDM4E | |
| Catechol SCHEMBL3985412 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TDP1ALOX15HSD17B10KDM4E | |
| Trientine SCHEMBL8562243 | 0.80 | CA12 (0.41) | ALDH1A1TDP1ALOX15HSD17B10KDM4E | |
| Dimethyl Sulfoxide SCHEMBL7629146 | 0.78 | — | — | |
| Orthocresol SCHEMBL10797190 | 0.76 | TAAR1 (0.45) | ALDH1A1TDP1ALOX15HSD17B10KDM4E | |
| Catechol SCHEMBL60031 | 0.75 | MAPT (0.67) | ALDH1A1TDP1ALOX15HSD17B10KDM4E | |
| Dimethyl Sulfoxide SCHEMBL2782633 | 0.75 | ALDH1A1 (0.53) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795702-A | MIXTURE OF HYDROXYLAMINE, WATER, AMINE, SOLVENT AND CORROSION INHIBITOR | TOKYO OHKA KOGYO CO, LTD. (JP) | 1998-08-18 | — | — | US | disclosed |