Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Catechol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Catechol SCHEMBL7740920 | 0.88 | TAAR1 (0.41) | TAAR1MEN1KMT2AKDM4EALDH1A1 | |
| Catechol SCHEMBL8565660 | 0.84 | ALDH1A1 (0.43) | TAAR1KDM4EALDH1A1IDO1TSHR | |
| Catechol SCHEMBL6689005 | 0.80 | ALDH1A1 (0.53) | MEN1KMT2AKDM4EALDH1A1IDO1 | |
| Catechol SCHEMBL3905550 | 0.80 | ALDH1A1 (0.53) | MEN1KMT2AKDM4EALDH1A1IDO1 | |
| Catechol SCHEMBL6887106 | 0.73 | ALDH1A1 (0.62) | MEN1KMT2AKDM4EALDH1A1IDO1 | |
| Di(Hydroxyethyl)Ether SCHEMBL10895949 | 0.73 | TSHR (0.62) | MEN1KMT2AALDH1A1TSHRMAPK1 | |
| Di(Hydroxyethyl)Ether SCHEMBL11559017 | 0.73 | TSHR (0.62) | MEN1KMT2AALDH1A1TSHRMAPK1 | |
| Catechol SCHEMBL8562155 | 0.72 | CA12 (0.40) | TAAR1MEN1KMT2AKDM4EALDH1A1 | |
| Catechol SCHEMBL2279087 | 0.71 | ALDH1A1 (0.59) | TAAR1KDM4EALDH1A1IDO1TSHR | |
| Triethylene Glycol SCHEMBL10894260 | 0.71 | MEN1 (0.65) | MEN1KMT2AALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795702-A | MIXTURE OF HYDROXYLAMINE, WATER, AMINE, SOLVENT AND CORROSION INHIBITOR | TOKYO OHKA KOGYO CO, LTD. (JP) | 1998-08-18 | — | — | US | disclosed |