SCHEMBL8565691

SCHEMBL8565691

CCS(=O)(=O)N(C(=O)c1ccc(Cl)cc1)c1cc(-c2c(C(F)(F)F)n(C)c(=O)[nH]c2=O)c(F)cc1C#N

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7030317 0.91 L3MBTL1 (0.38) MEN1KMT2A
SCHEMBL7033033 0.87 KMT2A (0.33) MEN1KMT2A
SCHEMBL7027781 0.86 KMT2A (0.32) MEN1KMT2A
SCHEMBL7026967 0.86 DRD2 (0.30) MEN1KMT2A
SCHEMBL7153242 0.86 KMT2A (0.32) MEN1KMT2A
SCHEMBL7031698 0.85
SCHEMBL8563957 0.85 AR (0.31)
SCHEMBL7027406 0.84 GPBAR1 (0.32)
SCHEMBL7032866 0.83 KMT2A (0.32) KMT2A
SCHEMBL7024135 0.82 KMT2A (0.32) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0827497-A1 SUBSTITUTED AMINOPHENYLURACILS AS HERBICIDES AND INSECTICIDES BAYER AG (DE) 1998-03-11 EP disclosed