Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10574075 | 0.86 | KCNH2 (0.42) | KCNH2TAAR1KCNA3APPLTA4H | |
| SCHEMBL12934278 | 0.85 | KCNH2 (0.50) | KCNH2TAAR1KCNA3APPRAB9A | |
| SCHEMBL4638723 | 0.81 | CYP3A4 (0.54) | APPLTA4HRAB9ASMN1; SMN2MAOB | |
| SCHEMBL9785559 | 0.76 | KCNH2 (0.46) | KCNH2TAAR1KCNA3APPRAB9A | |
| SCHEMBL9706436 | 0.76 | MAOB (0.57) | KCNH2APPRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10576186 | 0.76 | ALDH1A1 (0.45) | KCNH2KCNA3APPLTA4HRAB9A | |
| SCHEMBL13577190 | 0.76 | CACNA1C (0.46) | RAB9ASMN1; SMN2MAOBCA12CA1 | |
| SCHEMBL4638716 | 0.75 | MAOB (0.49) | MAOBHDAC6 | |
| SCHEMBL1721579 | 0.73 | ALDH1A1 (0.49) | TAAR1RAB9ASMN1; SMN2NPC1MAOB | |
| SCHEMBL17644774 | 0.72 | MAOB (0.68) | RAB9ASMN1; SMN2NPC1MAOBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849959-A | Derivatives of 2, 3, 6-trifluorophenols and a process for their preparation | CLARIANT GMBH (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0779263-A1 | New derivatives of 2,3,6-trifluorophenol and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-18 | — | — | EP | disclosed |