SCHEMBL8565820

SCHEMBL8565820

CC(=O)OC1COCC1OC(=O)C(C)Nc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Cl

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM7 Q14831 1/20 0.41
GRM4 Q14833 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8113222 0.88 GRM1 (0.37) GRM7GRM4
SCHEMBL10569089 0.83 GRM7 (0.46) GRM7GRM4
SCHEMBL8114867 0.80 IDH1 (0.30)
SCHEMBL8569183 0.77 PPOX (0.49)
SCHEMBL8565283 0.77 GRM7 (0.38) GRM7GRM4
SCHEMBL29077232 0.73 GRM7 (0.53) GRM7GRM4
SCHEMBL10575285 0.72 GRM7 (0.44) GRM7GRM4
SCHEMBL29077234 0.70 GRM7 (0.52) GRM7GRM4
SCHEMBL29077255 0.68 GRM7 (0.51) GRM7GRM4
SCHEMBL10573470 0.68 GRM7 (0.44) GRM7GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0548593-B1 Tetrahydrofuran derivative and herbicide containing the same as effective ingredient MITSUBISHI CHEM CORP (JP) 1998-04-22 EP disclosed
US-5405828-A Selective pre- and postemergence herbicides MITSUBISHI KASEI CORPORATION (JP) 1995-04-11 US disclosed
US-5324709-A Safety on crops MITSUBISHI KASEI CORPORATION (JP) 1994-06-28 US disclosed
EP-0548593-A1 Tetrahydrofuran derivative and herbicide containing the same as effective ingredient Mitsubishi Chemical Corporation (JP) 1993-06-30 EP disclosed