SCHEMBL8565849

SCHEMBL8565849

Cc1nc2cnccc2n1CCCC(=O)O.[NaH]

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 7/20 0.47
TBXAS1 P24557 3/20 0.43
ATM Q13315 1/20 0.42
FABP4 P15090 1/20 0.41
FABP5 Q01469 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8322125 0.91 L3MBTL1 (0.46) PTAFRATM
SCHEMBL8317845 0.86 PTAFR (0.44) PTAFR
SCHEMBL8321832 0.84 GAA (0.50) PTAFRTBXAS1
SCHEMBL8882903 0.82 PTAFR (0.49) PTAFR
SCHEMBL10387961 0.81 PTAFR (0.48) PTAFR
SCHEMBL28516010 0.81 LMNA (0.62) FABP4FABP5
SCHEMBL8883493 0.80 PTAFR (0.51) PTAFR
SCHEMBL7494924 0.79 RPS6KA5 (0.60) PTAFR
SCHEMBL9691244 0.79 KMT2A (0.57) PTAFRATM
SCHEMBL10388556 0.79 PTAFR (0.48) PTAFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0842175-A1 IMIDAZOPYRIDINE DERIVATIVES BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1998-05-20 EP disclosed
WO-1997006167-A1 IMIDAZOPYRIDINE DERIVATIVES BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1997-02-20 WO disclosed