SCHEMBL8565874

SCHEMBL8565874

CCCCO[Si](OCCCC)(OCCCC)OCCCC.CCO[Si](OCC)(OCC)OCC

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39
TSHR P16473 4/20 0.35
CYP3A4 P08684 3/20 0.35
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
LMNA P02545 1/20 0.32
ATM Q13315 1/20 0.31
CYP2D6 P10635 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL565284 1.00 ADRB2 (0.39) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL432981 1.00 ADRB2 (0.39) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL766206 1.00 ADRB2 (0.39) ADRB2ADRB1ADRB3TSHRCYP3A4
Water SCHEMBL27572370 0.97 ADRB2 (0.38) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL1608585 0.95 ADRB2 (0.36) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL1608586 0.95 ADRB2 (0.36) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL1609590 0.95 ADRB2 (0.36) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL10629447 0.92 THRB (0.35) TSHRCA1CA2THRB
SCHEMBL17644808 0.92 THRB (0.35) TSHRCA1CA2THRB
SCHEMBL1609030 0.92 THRB (0.35) TSHRCA1CA2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5714659-A HYDROALKYLATION OF C9+ AROMATIC COMPOUNDS TO A C6-C8 AROMATIC HYDROCARBON USING A MIXED OXIDE OF ALUMINA, BORIC OXIDE AND PROMOTER METAL OXIDE OF GROUP 6 OR 8; NONCOKING; CATALYST SELECTIVITY; DURABILITY; STABILITY PHILLIPS PETROLEUM COMPANY (US) 1998-02-03 US disclosed