Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | TOP2A | P11388 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.53 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565928 | 1.00 | KDM4E (0.60) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8568350 | 0.88 | KDM4E (0.64) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8565272 | 0.88 | KDM4E (0.64) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL5569676 | 0.87 | KDM4E (0.62) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL5569671 | 0.87 | KDM4E (0.62) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8567571 | 0.85 | ALDH1A1 (0.53) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8567580 | 0.85 | ALDH1A1 (0.53) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8563927 | 0.85 | KCNH2 (0.50) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8563936 | 0.85 | KCNH2 (0.50) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8564954 | 0.84 | ALDH1A1 (0.66) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559752-B1 | OPTICAL ISOMERS OF 7- 3-(1,1-DIALKYLMETHYL-1-AMINO-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 1998-01-28 | — | — | EP | disclosed |
| US-5364861-A | Bactericides with side effect reduction | WARNER-LAMBERT COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| US-5278317-A | Aminomethylpyrrole | WARNER-LAMBERT COMPANY (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0559752-A1 | OPTICAL ISOMERS OF 7- 3-(1,1-DIALKYLMETHYL-1-AMINO-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5157128-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1992-10-20 | — | — | US | disclosed |
| WO-1992009597-A1 | OPTICAL ISOMERS OF 7-[3-(1,1-DIALKYLMETHYL-1-AMINO-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1992-06-11 | — | — | WO | disclosed |
| US-5072001-A | Bactericides | WARNER-LAMBERT COMPANY (US) | 1991-12-10 | — | — | US | disclosed |