Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 4/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20224945 | 0.79 | LOXL2 (0.45) | LOXL2HSD17B10TDP1L3MBTL1HRH1 | |
| SCHEMBL22308478 | 0.77 | TDP1 (0.56) | LOXL2HSD17B10TDP1L3MBTL1TBXAS1 | |
| SCHEMBL12830256 | 0.77 | TDP1 (0.56) | LOXL2HSD17B10TDP1L3MBTL1TBXAS1 | |
| SCHEMBL31437678 | 0.73 | SIGMAR1 (0.50) | L3MBTL1 | |
| SCHEMBL12756358 | 0.72 | LOXL2 (0.42) | LOXL2HSD17B10TDP1L3MBTL1HRH1 | |
| SCHEMBL28733276 | 0.71 | LOXL2 (0.59) | LOXL2HSD17B10TDP1L3MBTL1HRH1 | |
| SCHEMBL17184443 | 0.69 | LOXL2 (0.61) | LOXL2HSD17B10TDP1L3MBTL1HRH1 | |
| SCHEMBL7075024 | 0.69 | LOXL2 (0.50) | LOXL2HSD17B10TDP1L3MBTL1TBXAS1 | |
| SCHEMBL9971270 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL18985059 | 0.67 | LOXL2 (0.59) | LOXL2HSD17B10TDP1L3MBTL1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5779934-A | FLUORINATING AN ALCOHOL DERIVATIVE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |