Benzil

Benzil

SCHEMBL8566209

COC(C)OC.O=C(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES2 O00748 13/20 0.61
CES1 P23141 12/20 0.61
MAPT P10636 3/20 0.53
NPSR1 Q6W5P4 2/20 0.53
LMNA P02545 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
XBP1 P17861 1/20 0.53
ATM Q13315 1/20 0.53
TSHR P16473 1/20 0.50
RAB9A P51151 2/20 0.48
HPGD P15428 2/20 0.47
NPC1 O15118 1/20 0.45
PAX8 Q06710 1/20 0.45
ALDH1A1 P00352 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KDM4E B2RXH2 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzil SCHEMBL5453800 0.94 CES2 (0.58) CES2CES1MAPTNPSR1LMNA
Benzophenone SCHEMBL5389322 0.87 ALDH1A1 (0.61) MAPTNPSR1LMNASMN1; SMN2ATM
Acetophenone SCHEMBL5398083 0.85 SMN1; SMN2 (0.52) CES2CES1MAPTNPSR1LMNA
Benzil SCHEMBL422981 0.84 CES2 (0.78) CES2CES1LMNATSHRRAB9A
Benzil SCHEMBL4440009 0.82 CES2 (0.67) CES2CES1MAPTNPSR1LMNA
Benzil SCHEMBL28144199 0.81 CES2 (0.74) CES2CES1MAPTNPSR1LMNA
Phenylglyoxal SCHEMBL8924305 0.80 TDP1 (0.67) MAPTLMNATSHRRAB9ANPC1
SCHEMBL1616834 0.80 ALDH1A1 (0.48) NPSR1SMN1; SMN2TSHRHPGDALDH1A1
Propiophenone SCHEMBL8072756 0.80 SMN1; SMN2 (0.56) CES2CES1MAPTNPSR1LMNA
Benzil SCHEMBL28144200 0.80 CES2 (0.64) CES2CES1MAPTNPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5009597-A High strength core; protective coating KULZER & CO. GMBH (DE) 1991-04-23 US claimed
US-4404073-A FLOCCULANTS; WATER TREATMENT; PURITY RHONE-POULENC INDUSTRIES (FR) 1983-09-13 US claimed
CN-105377453-B Direct platen with double-layer structure 扎伊罗技术股份公司 2019-08-13 CN disclosed
CN-105377453-A Directly printed panel having a two-layer design KRONOPLUS TECHNICAL AG 2016-03-02 CN disclosed
CN-1272361-C photosensitive resin, resin composition and cured product thereof NIPPON KAYAKU KK (JP) 2006-08-30 CN disclosed
CN-1639227-A Photosensitive resins, resin compositions and products of curing thereof NIPPON KAYAKU KK (JP) 2005-07-13 CN disclosed
CN-1177008-C Radiation-curable powder composition UCB 2004-11-24 CN disclosed
CN-1398285-A Radiation curable powder compsns UCB SA (BE) 2003-02-19 CN disclosed
US-5708051-A ACRYLATE MONOMER, SILICIC ACID FILLER WITH SHEET STRUCTURE HERAEUS KULZER GMBH (DE) 1998-01-13 US disclosed
US-5532105-A HAVING GOOD ADHESION TO PLATED COPPER HITACHI CHEMICAL COMPANY, LTD. (JP) 1996-07-02 US disclosed
US-5009597-A High strength core; protective coating KULZER & CO. GMBH (DE) 1991-04-23 US disclosed
EP-0326977-A2 Light-sensitive registration material in the form of a sheet BASF Aktiengesellschaft (DE) 1989-08-09 EP disclosed
EP-0316618-A2 Multilayer flat light sensitive registration material BASF Aktiengesellschaft (DE) 1989-05-24 EP disclosed
EP-0230300-A2 Compositions which are reticulable by means of photopolymerisation BASF Aktiengesellschaft (DE) 1987-07-29 EP disclosed
US-4674980-A CURING AGENTS DEN-MAT, INC. (US) 1987-06-23 US disclosed
US-4404073-A FLOCCULANTS; WATER TREATMENT; PURITY RHONE-POULENC INDUSTRIES (FR) 1983-09-13 US disclosed
US-4404073-A FLOCCULANTS; WATER TREATMENT; PURITY RHONE-POULENC INDUSTRIES (FR) 1983-09-13 US disclosed
US-4404073-A FLOCCULANTS; WATER TREATMENT; PURITY RHONE-POULENC INDUSTRIES (FR) 1983-09-13 US disclosed
US-4286008-A THE DESIGN LAYER COMPRISING A FLEXIBLE PHOTOPOLYMERIZED ACRYLIC INK BEING RESISTANT TO THE STRESS OF THE MECHANICAL FORCE OF A STYLUS E. T. MARLER LIMITED (GB) 1981-08-25 US disclosed