Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5883850 | 0.83 | — | — | |
| SCHEMBL19732852 | 0.79 | HSP90AA1 (0.41) | HSP90AA1P2RX7CYP2D6 | |
| SCHEMBL22110815 | 0.79 | HSP90AA1 (0.37) | HSP90AA1P2RX7CYP2D6RXRAGRIN1 | |
| SCHEMBL17591561 | 0.79 | ALDH1A1 (0.39) | HSP90AA1P2RX7CYP2D6RXRAGRIN1 | |
| SCHEMBL6638944 | 0.78 | CYP2D6 (0.57) | CYP2D6CYP19A1 | |
| SCHEMBL27890075 | 0.76 | LOX (0.39) | HSP90AA1P2RX7CYP2D6RXRAGRIN1 | |
| SCHEMBL27928341 | 0.74 | — | — | |
| SCHEMBL27953989 | 0.74 | — | — | |
| SCHEMBL16399201 | 0.74 | — | — | |
| SCHEMBL27916645 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586393-B1 | SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES | ZENECA LTD (GB) | 1998-06-17 | — | — | EP | disclosed |
| US-5439910-A | For applying to plants, seeds or soils | ZENECA LIMITED (GB) | 1995-08-08 | — | — | US | disclosed |
| EP-0586393-A1 | SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES | ZENECA LIMITED (GB) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992018487-A1 | SUBSTITUTED-2-PHENYL-3-METHOXYPROPENOATES AS FUNGICIDES | ZENECA LIMITED (GB) | 1992-10-29 | — | — | WO | disclosed |