Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499783 | 0.78 | ALDH1A1 (0.39) | CYP2A6KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL8562276 | 0.73 | CYP2A6 (0.47) | CYP2A6KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL1597577 | 0.72 | BCHE (0.46) | BCHEACHEKDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11604764 | 0.71 | BCHE (0.45) | BCHEACHEKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23143409 | 0.70 | BCHE (0.60) | BCHEACHESMN1; SMN2PDGFRBPDGFRA | |
| SCHEMBL10960575 | 0.69 | KDM4E (0.72) | CYP2A6KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL2928822 | 0.69 | BCHE (0.46) | BCHEACHEKDM4EALDH1A1MAPT | |
| SCHEMBL9908948 | 0.68 | BCHE (0.65) | BCHEACHEALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9908947 | 0.68 | BCHE (0.57) | BCHEACHEKDM4EALDH1A1MAPT | |
| SCHEMBL12986794 | 0.68 | BCHE (0.57) | BCHEACHEMAPTSMN1; SMN2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795889-A | INHIBITING CELL GROWTH WITH ENZYME INHIBITORS FOR SKIN DISORDERS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-08-18 | — | — | US | disclosed |
| US-5646153-A | INHIBITING ABNORMAL CELL PROLIFERATION | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5480883-A | Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-01-02 | — | — | US | disclosed |