Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566360 | 1.00 | ALDH1A1 (0.46) | ALDH1A1NPC1PDE10ALMNAMEN1 | |
| SCHEMBL1092487 | 0.80 | PDE10A (0.49) | ALDH1A1NPC1PDE10ALMNAMEN1 | |
| SCHEMBL1092129 | 0.80 | PDE10A (0.49) | ALDH1A1NPC1PDE10ALMNAMEN1 | |
| SCHEMBL1092131 | 0.80 | PDE10A (0.49) | ALDH1A1NPC1PDE10ALMNAMEN1 | |
| SCHEMBL8567625 | 0.79 | KMT2A (0.41) | ALDH1A1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL8567627 | 0.79 | KMT2A (0.41) | ALDH1A1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL9000299 | 0.78 | PDE10A (0.54) | ALDH1A1NPC1PDE10ALMNAMEN1 | |
| SCHEMBL8561899 | 0.76 | PDE10A (0.49) | ALDH1A1NPC1PDE10ALMNAMEN1 | |
| SCHEMBL13351976 | 0.76 | PDE10A (0.49) | ALDH1A1NPC1PDE10ALMNAMEN1 | |
| SCHEMBL8561898 | 0.76 | PDE10A (0.49) | ALDH1A1NPC1PDE10ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |