Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.35 |
| ▸ | RARB | P10826 | 4/20 | 0.35 |
| ▸ | RARG | P13631 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | GOT1 | P17174 | 1/20 | 0.35 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 5/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394301 | 0.88 | HIF1A (0.36) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL8565823 | 0.87 | RARA (0.42) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL8567793 | 0.86 | IKBKB (0.42) | RARARARGLMNAHIF1AEPAS1 | |
| SCHEMBL8397842 | 0.82 | MEN1 (0.31) | MEN1KMT2AIKBKB | |
| SCHEMBL8568404 | 0.80 | IKBKB (0.35) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL8572746 | 0.78 | CNR2 (0.42) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL8573235 | 0.77 | RARA (0.41) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL8574908 | 0.76 | IKBKB (0.33) | RARALMNAHIF1AEPAS1IKBKB | |
| SCHEMBL8575216 | 0.75 | IKBKB (0.34) | RARAMEN1LMNAKMT2AHIF1A | |
| SCHEMBL8433273 | 0.75 | RARA (0.45) | RARARARBRARGMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | claimed |
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |