Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.35 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574908 | 0.94 | IKBKB (0.33) | IKBKBHIF1AEPAS1RARALMNA | |
| SCHEMBL8575216 | 0.89 | IKBKB (0.34) | IKBKBHIF1AEPAS1RARAKDM4E | |
| SCHEMBL8566523 | 0.88 | IKBKB (0.32) | IKBKBRARAKMT2AMEN1 | |
| SCHEMBL8394301 | 0.86 | HIF1A (0.36) | IKBKBHIF1AEPAS1RARAKDM4E | |
| SCHEMBL8570620 | 0.86 | IKBKB (0.31) | IKBKB | |
| SCHEMBL8568790 | 0.85 | IKBKB (0.31) | IKBKBRARA | |
| SCHEMBL8570993 | 0.83 | RARA (0.37) | IKBKBHIF1AEPAS1RARAKDM4E | |
| SCHEMBL8567726 | 0.83 | CNR2 (0.41) | HIF1AEPAS1RARAKDM4ELMNA | |
| SCHEMBL8570424 | 0.82 | CNR2 (0.40) | IKBKBHIF1AEPAS1RARAKDM4E | |
| SCHEMBL8573237 | 0.82 | CNR2 (0.33) | IKBKBHIF1AEPAS1RARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | claimed |
| US-5827500-A | TOPICAL SKIN TESTING THE ANIMAL RESPONSES BY APPLYING RETINOIC ACID RECEPTOR AGONIST AND ANTAGONIST | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-10-27 | — | — | US | disclosed |
| US-5798354-A | COSMETIC, THERAPY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-08-25 | — | — | US | disclosed |